ObjectiveTo explore the effective components and mechanism of Polygonati Rhizoma (PR) in the treatment of osteoporosis (OP) based on network pharmacology and molecular docking methods.MethodsThe effective components and predicted targets of PR were obtained through the Traditional Chinese Medicine Systems Pharmacology and Analysis Platform (TCMSP)

Sea Echinamide Immune Burst Punch sticking is a common tablet compression manufacturing issue experienced during late-stage large-scale manufacturing.Prediction of punch sticking propensity and identification of the sticking component is important for early-stage formulation development.Application of novel predictive capabilities offers early-stag

Objective: To investigate the effect of the screw configuration on the polylactic acid flow field on the structural parameters of the screw on the end face of the screw in the meshing counter rotating twin screw extruder.Methods: The theoretical model of the heterodirectional double-ended threaded element was established by Solidworks software and

The Flameless Candles arrival of the cholera epidemic in Elche, a western Mediterranean city during 1884-85, produces a set of responses: Urban changes, improvements in public health, denunciation from the press, and, above all, the development of the pro-union associative movement.The objective of this article is to interpret these Biography respo

Intensive and massive coal mining causes a series of geological hazards and environmental problems, especially surface subsidence.At present, two major types of subsidence control technology are applied: backfilling technology and partial mining technology.However, the cost of backfill mining is high and partial mining has a low recovery ratio.Ther